Baclofen is medication that is commonly used to control spasticity related to multiple sclerosis, spinal cord injury, or other neurological diseases. It is difficult to increase the dosage of baclofen if it is taken orally due to side effects like sleepiness. Besides, when baclofen is administered orally, only a small portion of the original dose crosses the blood brain barrier and enters the central nervous system (CNS) fluid, which is the site of drug action. In order to bypass the oral route, baclofen may be administered intrathecally by infusion directly to the CNS. Therefore implantation of a pump under the skin is necessary to deliver the baclofen directly to the spinal cord.

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